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mm cannabis sativa seed oil side effects

Mm cannabis sativa seed oil side effects

CBD is the short name for cannabidiol , one of the two chemicals in cannabis with the most health benefits. The other chemical is tetrahydrocannabinol (THC).

This cannabis extract may help treat nerve pain, anxiety, and epilepsy

Don’t take CBD oil if you’re pregnant or breastfeeding. The American Academy of Pediatrics advises pregnant women to avoid marijuana because of the potential risks to a baby’s development. Although the effects of CBD itself are unclear, CBD does pass through the placenta.

Recap

Unlike THC, CBD doesn’t have a strong connection with cannabinoid receptors in the brain. These are the molecules that THC binds to create psychoactive effects.

Cannabidiol (CBD), a major nonpsychotropic constituent of Cannabis, has multiple pharmacological actions, including anxiolytic, antipsychotic, antiemetic and anti-inflammatory properties. However, little is known about its safety and side effect profile in animals and humans. This review describes in vivo and in vitro reports of CBD administration across a wide range of concentrations, based on reports retrieved from Web of Science, Scielo and Medline. The keywords searched were “cannabinoids”, “cannabidiol” and “side effects”. Several studies suggest that CBD is non-toxic in non-transformed cells and does not induce changes on food intake, does not induce catalepsy, does not affect physiological parameters (heart rate, blood pressure and body temperature), does not affect gastrointestinal transit and does not alter psychomotor or psychological functions. Also, chronic use and high doses up to 1,500 mg/day of CBD are reportedly well tolerated in humans. Conversely, some studies reported that this cannabinoid can induce some side effects, including inhibition of hepatic drug metabolism, alterations of in vitro cell viability, decreased fertilization capacity, and decreased activities of p-glycoprotein and other drug transporters. Based on recent advances in cannabinoid administration in humans, controlled CBD may be safe in humans and animals. However, further studies are needed to clarify these reported in vitro and in vivo side effects.